The value of 3D pseudo-continuousarterial spin labeling perfusion imaging in moyamoya disease-Comparison with dynamic susceptibility contrast perfusion imaging.

ABSTRACT:

Background and purpose

3D pseudo-continuous arterial spin labeling (3D pCASL) is commonly used to measure arterial cerebral blood flow (CBF). The aim of this study was to assess the clinical feasibility and accuracy of 3D pCASL in comparison with dynamic susceptibility contrast (DSC) perfusion imaging in moyamoya disease (MMD).

Materials and methods

A total of 174 MMD patients underwent 3D pCASL and DSC-MRI for evaluating cerebral blood perfusion. 3D-pCASL with two single post-labeling delay (PLD) times (1,500 and 2,500 ms) was used to measure CBF. The values of DSC-CBF and ASL-CBF were calculated for major arterial territories including the anterior, middle, and posterior cerebral arteries as well as the areas based on the Alberta Stroke Program Early CT Score (ASPECTS) tem

SUBMITTER: Zhang H 

PROVIDER: S-EPMC9389231 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature