Rabbit targeted genomic sequences after heterologous hybridization using human exome.

ABSTRACT:

Objective

Causal mutations for major genes that underlie a broad range of morphological traits are often located within exons of genes that then affect protein functions. Non-model organism genetic studies are not easy to perform due to the lack of genome-wide molecular tools such as SNP genotyping array. Genotyping-By-Sequencing (GBS) methods offer an alternative. Consequently, we used this approach that is focused on the exome to target and identify major genes in rabbit populations. Data description We used a heterologous enrichment method before sequencing, allowing us to capture the rabbit exome using the marketed human panel since mammal protein coding genes are well conserved across the phylogenic tree of species. This targeted strategy was performed on 52 French rabbits fro

SUBMITTER: Iannuccelli N 

PROVIDER: S-EPMC9389681 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature