Modeled microgravity alters apoptotic gene expression and caspase activity in the squid-vibrio symbiosis.

ABSTRACT:

Background

Spaceflight is a novel and profoundly stressful environment for life. One aspect of spaceflight, microgravity, has been shown to perturb animal physiology thereby posing numerous health risks, including dysregulation of normal developmental pathways. Microgravity can also negatively impact the interactions between animals and their microbiomes. However, the effects of microgravity on developmental processes influenced by beneficial microbes, such as apoptosis, remains poorly understood. Here, the binary mutualism between the bobtail squid, Euprymna scolopes, and the gram-negative bacterium, Vibrio fischeri, was studied under modeled microgravity conditions to elucidate how this unique stressor alters apoptotic cell death induced by beneficial microbes.

Results

Ana

SUBMITTER: Vroom MM 

PROVIDER: S-EPMC9389742 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature