A randomized double blind comparison of atosiban in patients with recurrent implantation failure undergoing IVF treatment.

ABSTRACT:

Background

Patients with recurrent implantation failure (RIF) may have more uterine contractions. Several observational studies suggested that atosiban administration around embryo transfer resulted in higher pregnancy rates in RIF patients. This study aimed to evaluate the effect of atosiban given before fresh embryo transfer on pregnancy outcomes of women with RIF.

Methods

A prospective, randomized, double-blind controlled clinical trial was performed in IVF center of Shanghai First Maternity and Infant Hospital. According to a computer-generated randomization list, 194 infertile women with RIF received fresh embryo transfer between July 2017 and December 2019 were randomly allocated into the atosiban (n = 97) and the placebo (n = 97) groups. Women in the treatment group r

SUBMITTER: Tang CL 

PROVIDER: S-EPMC9389813 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature