An advanced universal circulatory assist device for left and right ventricular support: First report of an acute in vivo implant.

ABSTRACT:

Background

The Advanced ventricular assist device (Advanced VAD) is designed as a universal pump intended to prevent backflow in the event of pump stoppage, to maintain physiological pulse pressure, and to be used as both a left and right VAD. The purpose of this study was to evaluate the performance of the Advanced VAD as both a left and right VAD in an acute in vivo study in calves.

Methods

The Advanced VAD was implanted through a median sternotomy in 5 healthy calves (weight, 71.4-91.2 kg) as a left VAD (n = 3) or a right VAD (n = 2). After implantation, hemodynamic parameters, including general performance and pump stoppage, were evaluated.

Results

The Advanced VAD was successfully implanted as a left and right VAD without cardiopulmonary bypass. The speed range o

SUBMITTER: Miyamoto T 

PROVIDER: S-EPMC9390363 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature