Warm versus cold cardioplegia in cardiac surgery: A meta-analysis with trial sequential analysis.

ABSTRACT:

Objective

This meta-analysis aimed to compare clinical outcomes of warm and cold cardioplegia in cardiac surgeries in adult patients, with trial sequential analysis (TSA) used to determine the conclusiveness of the results.

Methods

Electronic searches were performed on PubMed, Medline, Scopus, EMBASE, and Cochrane library to identify all studies that compared warm and cold cardioplegia in cardiac surgeries. Primary end points were in-hospital or 30-day mortality, myocardial infarction, low cardiac output syndrome, intra-aortic balloon pump use, stroke, and new atrial fibrillation. Secondary end points were acute kidney injury, hospital length of stay, and intensive care unit length of stay. Prespecified subgroup analyses were performed for (1) studies published since publica

SUBMITTER: Kot TKM 

PROVIDER: S-EPMC9390447 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature