Conventional versus miniaturized cardiopulmonary bypass: A systematic review and meta-analysis.

ABSTRACT:

Objective

A meta-analysis of randomized controlled trials was performed to compare the effects of miniaturized extracorporeal circulation (MECC) and conventional extracorporeal circulation (CECC) on morbidity and mortality rates after cardiac surgery.

Methods

A comprehensive literature search was conducted using Ovid, PubMed, Medline, EMBASE, and the Cochrane databases. Randomized controlled trials from the year 2000 with n > 40 patients were considered. Key search terms included variations of "mini," "cardiopulmonary," "bypass," "extracorporeal," "perfusion," and "circuit." Studies were assessed for bias using the Cochrane Risk of Bias tool. The primary outcomes were postoperative mortality and stroke. Secondary outcomes included arrhythmia, myocardial infarction, renal fai

SUBMITTER: Cheng T 

PROVIDER: S-EPMC9390465 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature