Right lung transplantation with a left-to-right inverted anastomosis in a rat model.

ABSTRACT:

Objective

Right lung transplantation in rats has been attempted occasionally, but the technical complexity makes it challenging to apply routinely. Additionally, basic research on inverted lobar lung transplantation is scarce because of the lack of a cost-effective experimental model. We first reported right lung transplantation in a rat model using left-to-right inverted anastomosis to imitate the principle of clinically inverted lung transplantation.

Methods

Right lung transplantation was performed in 10 consecutive rats. By using a 3-cuff technique, the left lung of the donor rat was implanted into the right thoracic cavity of the recipient rat. The rat lung graft was rotated 180° along the vertical axis to achieve anatomic matching of right hilar structures. Another 10 c

SUBMITTER: Huang H 

PROVIDER: S-EPMC9390618 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature