Adhering to guideline concordant care improves survival among the different subtypes of T3 N2 non-small cell lung cancer.

ABSTRACT:

Objectives

T3 disease comprises heterogeneous morphologic characteristics, a variation only further complicated when in the context of N2-confirmed involvement. This study aims to examine whether or not specific features of T3 N2 non-small cell lung cancer are associated with improved 5-year overall survival when using a multimodal therapeutic approach consistent with guideline recommendations compared with definitive surgery alone.

Methods

Patients with pathologic T3 N2 non-small cell lung cancer were identified in the National Cancer Database. Therapy modality, as defined by surgery alone versus surgery with adjuvant therapy, and T3 disease descriptors were compared for differences in 5-year overall survival using Kaplan-Meier analysis and log-rank tests. Multivariable Cox

SUBMITTER: Wang JC 

PROVIDER: S-EPMC9390621 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature