Prediction of aortic dilatation in surgically repaired type A dissection: A longitudinal study using computational fluid dynamics.

ABSTRACT:

Objective

To examine the role of a key hemodynamic parameter, namely the true and false lumen pressure difference, to predict progressive aortic dilatation following type A aortic dissection (TAAD) repair.

Methods

Four patients with surgically repaired TAAD with multiple follow-up computed tomography angiography scans (4-5 scans per patient; N = 18) were included. Through-plane diameter of the residual native thoracic aorta was measured in various aortic segments during the follow up period (mean follow-up: 49.6 ± 31.2 months). Computational flow analysis was performed to estimate true and false lumen pressure difference at the same locations and the correlation with aortic size change was studied using a linear mixed effects model.

Results

Greater pressure difference

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC9390758 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature