Assessing the impact of Ascariasis and Trichuriasis on weight gain using a porcine model.

ABSTRACT:

Background

Infections with Ascaris lumbricoides and Trichuris trichiura remain significant contributors to the global burden of neglected tropical diseases. Infection may in particular affect child development as they are more likely to be infected with T. trichiura and/or A. lumbricoides and to carry higher worm burdens than adults. Whilst the impact of heavy infections are clear, the effects of moderate infection intensities on the growth and development of children remain elusive. Field studies are confounded by a lack of knowledge of infection history, nutritional status, presence of co-infections and levels of exposure to infective eggs. Therefore, animal models are required. Given the physiological similarities between humans and pigs but also between the helminths that infec

SUBMITTER: Whitehead B 

PROVIDER: S-EPMC9390923 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature