Symptom Trajectories of Early Responders and Remitters among Youth with OCD.

ABSTRACT:

Objectives

This study examined the phenomenology and predictors of early response and remission among youth with obsessive-compulsive disorder (OCD) receiving cognitive-behavioral therapy (CBT).

Methods

One hundred and thirty-nine youth with a current primary diagnosis of OCD participated in this study. Participants received 10 sessions of CBT augmented by either placebo or d-cycloserine (DCS) as part of a randomized double-blind multi-site clinical trial. Early response and remission status were determined by clinician-rated global symptom improvement (CGI-I) and severity (CGI-S), respectively.

Results

At the mid-treatment assessment, 45.3% of youth were early responders, and 28.1% were early remitters. At post-treatment assessment, 79.1% of youth were responders and

SUBMITTER: Rech M 

PROVIDER: S-EPMC9390966 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature