Plasma sICAM-1 as a Biomarker of Carotid Plaque Inflammation in Patients with a Recent Ischemic Stroke.

ABSTRACT: ¹⁸F-fluorodeoxyglucose positron emission tomography (¹⁸F-FDG PET) identifies carotid plaque inflammation and predicts stroke recurrence in patients with atherothrombotic stroke. The aim of the study was to identify plasma inflammatory biomarkers associated with plaque inflammation according to ¹⁸F-FDG uptake. We conducted a prospective study of consecutive adult patients with a recent (< 7 days) anterior circulation ischemic stroke and at least one atherosclerotic plaque in the ipsilateral internal carotid artery. We included 64 patients, 57.8% of whom showed a carotid stenosis ≥ 50%. All patients underwent an early (< 15 days from inclusion) ¹⁸F-FDG PET, and a blood sample was obtained at days 7 ± 1 from the stroke. The plasma concentration of 1

SUBMITTER: Puig N 

PROVIDER: S-EPMC9391243 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature