Analysis of individual differences in neurofeedback training illuminates successful self-regulation of the dopaminergic midbrain.

ABSTRACT: The dopaminergic midbrain is associated with reinforcement learning, motivation and decision-making - functions often disturbed in neuropsychiatric disorders. Previous research has shown that dopaminergic midbrain activity can be endogenously modulated via neurofeedback. However, the robustness of endogenous modulation, a requirement for clinical translation, is unclear. Here, we examine whether the activation of particular brain regions associates with successful regulation transfer when feedback is no longer available. Moreover, to elucidate mechanisms underlying effective self-regulation, we study the relation of successful transfer with learning (temporal difference coding) outside the midbrain during neurofeedback training and with individual reward sensitivity in a monetary incentive

SUBMITTER: Hellrung L 

PROVIDER: S-EPMC9391365 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature