Catalytic synthesis of new pyrazolo [3,4-b] pyridine via a cooperative vinylogous anomeric-based oxidation.

ABSTRACT: In this study, a novel nano-magnetic metal-organic frameworks based on Fe₃O₄ namely Fe₃O₄@MIL-101(Cr)-N(CH₂PO₃)₂ was synthesized and fully characterized. The prepared sample was used as catalyst in the synthesis of pyrazolo [3,4-b] pyridines as convenient medicine by condensation reaction of aldehydes, 5-(1H-Indol-3-yl)- 2H-pyrazol-3-ylamine and 3-(cyanoacetyl)indole via a CVABO. The products were obtained with high yields at 100 °C and under solvent-free conditions.

SUBMITTER: Sepehrmansourie H 

PROVIDER: S-EPMC9391453 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature