[Remifentanil-ketamine vs. propofol-ketamine for sedation in pediatric patients undergoing colonoscopy: A randomized clinical trial].

ABSTRACT:

Background and objectives

Pediatric patients frequently require deep sedation or general anesthesia for colonoscopy. This study was designed to compare the sedative efficacy of remifentanil-ketamine combination with propofol-ketamine combination in children undergoing colonoscopy.

Methods

Seventy patients, between 2 and 16 years of age, scheduled for diagnostic colonoscopy were randomly allocated into two groups. Remifentanil-ketamine group received intravenous ketamine 2mg.kg^-1 and remifentanil 0.25μg.kg^-1 combination, followed by 0.1μg.kg^-1.min^-1 remifentanil infusion. Propofol-ketamine group received intravenous propofol 1 and 2mg.kg^-1 ketamine combination, followed by 1mg.kg^-1.h^-1 propofol infus

SUBMITTER: Karacaer F 

PROVIDER: S-EPMC9391731 | biostudies-literature | 2018 Nov - Dec

REPOSITORIES: biostudies-literature