[The influence of the menstrual cycle on acute and persistent pain after laparoscopic cholecystectomy].

ABSTRACT:

Background and objectives

Fluctuations of female sex hormones during menstrual cycle influence pain perception. Endogenous pain inhibition is impaired in follicular phase of menstrual cycle. We tested the primary hypothesis that the women having surgery during their follicular phase have more acute pain and require higher opioids than those in the luteal phase, and secondarily we tested that women who have surgery during their follicular phase have more incisional pain at 3 month postoperatively.

Methods

127 adult females having laparoscopic cholecystectomy were randomized to have surgery during the luteal or follicular phase of their menstrual cycle. Standardized anesthesia and pain management regimen was given to all patients. Pain and analgesic consumption were evaluated

SUBMITTER: Sari S 

PROVIDER: S-EPMC9391774 | biostudies-literature | 2018 May - Jun

REPOSITORIES: biostudies-literature