[Combination of clonidine-bupivacaine in caudal epidural anesthesia for hypospadias surgery in children: prospective, randomized, blind study].

ABSTRACT:

Background and objectives

The combination of clonidine with local anesthetic administered for epidural anesthesia via caudal route seems to improve the quality of postoperative analgesia, but with conflicting results. This study compared the postoperative analgesia of three different doses of clonidine combined with bupivacaine in caudal epidural anesthesia in children undergoing hypospadias repair.

Methods

Eighty children aged 1 to 10 years, candidates for surgical repair of hypospadias, were randomly divided into four groups of 20 patients to receive general anesthesia combined with caudal epidural anesthesia with bupivacaine 0.165% alone or in combination with 1, 2 or 3μg.kg^-1 of clonidine. The primary outcome was morphine consumption in the first 24

SUBMITTER: Bonisson ACM 

PROVIDER: S-EPMC9391797 | biostudies-literature | 2019 Jan - Feb

REPOSITORIES: biostudies-literature