[Preemptive nebulized ketamine for pain control after tonsillectomy in children: randomized controlled trial].

ABSTRACT:

Objectives

The administration of ketamine as nebulized inhalation is relatively new and studies on nebulized ketamine are scarce. We aimed to investigate the analgesic efficacy of nebulized ketamine (1 and 2mg.kg^-1) administered 30min before general anesthesia in children undergoing elective tonsillectomy in comparison with intravenous ketamine (0.5mg.kg^-1) and saline placebo.

Methods

One hundred children aged (7-12) years were randomly allocated in four groups (n=25) receive; Saline Placebo (Group C), Intravenous Ketamine 0.5mg.kg^-1 (Group K-IV), Nebulized Ketamine 1mg.kg^-1 (Group K-N1) or 2mg.kg^-1 (Group K-N2). The primary endpoint was the total consumption of rescue analgesics in the first 24h postoperative.

Result

SUBMITTER: Abdel-Ghaffar HS 

PROVIDER: S-EPMC9391877 | biostudies-literature | 2019 Jul - Aug

REPOSITORIES: biostudies-literature