Cost minimization analysis of an in-house molecular test for cytomegalovirus in relation to a commercial molecular system.

ABSTRACT:

Introduction

Cytomegalovirus may cause severe disease in immunocompromised patients. Nowadays, quantitative polymerase chain reaction is the gold-standard for both diagnosis and monitoring of cytomegalovirus infection. Most of these assays use cytomegalovirus automated molecular kits which are expensive and therefore not an option for small laboratories, particularly in the developing world.

Objective

This study aimed to optimize and validate an in-house cytomegalovirus quantitative polymerase chain reaction test calibrated using the World Health Organization Standards, and to perform a cost-minimization analysis, in comparison to a commercial cytomegalovirus quantitative polymerase chain reaction test.

Study design

The methodology consisted of determining: optimizati

SUBMITTER: Caurio CFB 

PROVIDER: S-EPMC9392125 | biostudies-literature | 2020 May - Jun

REPOSITORIES: biostudies-literature