Clinical outcomes of multifocal papillary thyroid cancer: A systematic review and meta-analysis.

ABSTRACT:

Objective

Papillary thyroid cancer (PTC) is the most common endocrine malignancy with a steadily increasing incidence. Researches have reported that tumor multifocality occurs in an extensive number of cases. Nevertheless, the clinical characteristics and prognostic value remained controversial. This study was performed to investigate the relationship between multifocal PTC and adverse clinicopathologic features and the prognosis.

Methods

A systematic review and meta-analysis were conducted based on three electronic databases up to December 31, 2021. Parameters of interest included five clinical features (extrathyroidal extension, lymphovascular invasion, central lymph node metastasis, lateral lymph node metastasis, distant metastasis) and were pooled into risk ratios (RRs).

SUBMITTER: Cui L 

PROVIDER: S-EPMC9392403 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature