Epilepsy in patients with congenital heart disease: A nationwide cohort study.

ABSTRACT:

Background

Congenital heart disease (CHD) is the most common congenital defect, and reports suggest an increased risk of subsequent epilepsy. We used Swedish comprehensive population-based registers to investigate the risk of epilepsy in patients with CHD compared to matched controls and identify underlying factors of epilepsy.

Methods

All patients with CHD born between 1970 and 2017 and 10 age- and sex-matched controls were included. Epilepsy was ascertained by International Statistical Classification of Diseases and Related Health Problems codes, and the cumulative hazard of epilepsy was described using Cox regression.

Results

The study cohort consisted of 71,941 patients with CHD and 714,462 matched controls. The cumulative incidence of epilepsy in the study period

SUBMITTER: Zelano J 

PROVIDER: S-EPMC9392522 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature