Structural disconnectome mapping of cognitive function in poststroke patients.

ABSTRACT:

Background and purpose

Sequalae following stroke represents a significant challenge in current rehabilitation. The location and size of focal lesions are only moderately predictive of the diverse cognitive outcome after stroke. One explanation building on recent work on brain networks proposes that the cognitive consequences of focal lesions are caused by damages to anatomically distributed brain networks supporting cognition rather than specific lesion locations.

Methods

To investigate the association between poststroke structural disconnectivity and cognitive performance, we estimated individual level whole-brain disconnectivity probability maps based on lesion maps from 102 stroke patients using normative data from healthy controls. Cognitive performance was assessed in t

SUBMITTER: Kolskar KK 

PROVIDER: S-EPMC9392540 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature