Gene-diet interactions and cardiovascular diseases: a systematic review of observational and clinical trials.

ABSTRACT:

Background

Both genetic background and diet are important determinants of cardiovascular diseases (CVD). Understanding gene-diet interactions could help improve CVD prevention and prognosis. We aimed to summarise the evidence on gene-diet interactions and CVD outcomes systematically.

Methods

We searched MEDLINE^® via Ovid, Embase, PubMed^®, and The Cochrane Library for relevant studies published until June 6th 2022. We considered for inclusion cross-sectional, case-control, prospective cohort, nested case-control, and case-cohort studies as well as randomised controlled trials that evaluated the interaction between genetic variants and/or genetic risk scores and food or diet intake on the risk of related outcomes, including myocardial infarction, coronary

SUBMITTER: Roa-Diaz ZM 

PROVIDER: S-EPMC9392936 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature