Dynamic changes of quality of life in muscle-invasive bladder cancer survivors.

ABSTRACT:

Background

To explore the dynamic changes and effects of radical cystectomy on quality of life in muscle-invasive bladder cancer survivors.

Methods

Patients with muscle-invasive bladder cancer were randomly recruited in this study. We used the World Health Organization Quality of Life-Brief questionnaire to assess consecutive patients' quality of life. We applied kernel smoothing to illustrate the dynamic changes of the domain and item scores after treatment. Mixed-effects models were constructed to determine the effects of radical cystectomy on the scores of each item and domain of the World Health Organization Quality of Life-Brief questionnaire after controlling demographic and clinical factors.

Results

We collected 397 repeated measurements of the World Health Org

SUBMITTER: Tsai YS 

PROVIDER: S-EPMC9392945 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature