Impact of time to first relapse on long-term outcome in adult retroperitoneal sarcoma patients after radical resection.

ABSTRACT:

Background

Local recurrence of primary retroperitoneal sarcoma (RPS) is one of the major causes of treatment failure and death. We attempted to assess the effects of time to local recurrence (TLR) on the survival after recurrence (SAR) and overall survival (OS) of RPS.

Methods

Included in this study were 224 patients who underwent R0 resection for primary RPS at our institution between January 2000 and December 2020, 118 of whom had local recurrence. Based on the median TLR (19.8 months), patients were divided into two groups: early local recurrence (ELR < 20 months) and late local recurrence (LLR > 20 months). The Kaplan-Meier method was employed to calculate the local recurrence-free survival (LRFS), SAR and OS. Univariate and multivariate analyses were conducted to explor

SUBMITTER: Guan H 

PROVIDER: S-EPMC9393154 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature