Risk factors for severe COVID-19 in people with cystic fibrosis: A systematic review.

ABSTRACT:

Background

People with cystic fibrosis (CF) are considered a clinically fragile population with an intrinsic higher risk of developing severe COVID-19, though a certain variability in terms of outcomes and hospitalization has been noticed.

Aim

To highlight the main risk factors for severe COVID-19 in patients with CF.

Methods

A systematic review of the current literature was conducted through PubMed and EMBASE databases. English-written articles reporting clinical data on CF subjects with SARS-CoV2 infection were included and analyzed. Selected reports were evaluated for adherence to STROBE recommendations.

Results

After the selection phase, 9 observational studies were included, 5 of which reported data from CF Registry Global Harmonization Group. The hospital

SUBMITTER: Terlizzi V 

PROVIDER: S-EPMC9393295 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature