Volumetric modulated arc therapy versus tomotherapy for late T-stage nasopharyngeal carcinoma.

ABSTRACT:

Purpose

To compare the dosimetric parameters and clinical outcomes between volumetric modulated arc therapy (VMAT) and tomotherapy for treating late T-stage nasopharyngeal carcinoma (NPC).

Methods

Patients with non-metastatic late T-stage NPC who received definitive radiotherapy with tomotherapy or VMAT were selected. 1:1 propensity score matching (PSM) was used to control the balance of confounding factors. The dosimetric parameters and clinical outcomes were compared.

Results

A total of 171 patients were enrolled before matching, with 61 patients in the VMAT group and 110 patients in the tomotherapy group. In the post-PSM cohort, 54 sub-pairs of 108 patients were included after matching. Tomotherapy was superior to VMAT in the dosimetric parameters of planning targe

SUBMITTER: Chen Q 

PROVIDER: S-EPMC9393424 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature