Sex Differences in Active Pulmonary Tuberculosis Outcomes in Mali, West Africa.

ABSTRACT: Men and women often respond differently to infectious diseases and their treatments. Tuberculosis (TB) is a life-threatening communicable disease that affects more men than women globally. Whether male sex is an independent risk factor for unfavorable TB outcomes, however, has not been rigorously investigated in an African context, where individuals are likely exposed to different microbial and environmental factors. We analyzed data collected from a cohort study in Mali by focusing on newly diagnosed active pulmonary TB individuals who were treatment naive. We gathered baseline demographic, clinical, and microbiologic characteristics before treatment initiation and also at three time points during treatment. More males than females were affected with TB, as evidenced by a male-to-female r

SUBMITTER: Dabitao D 

PROVIDER: S-EPMC9393465 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature