Establishing evidence-based pharmacologic treatments for neonatal abstinence syndrome: A retrospective case study.

ABSTRACT: Translation of research discoveries into health impact can take many years, creating delays in improving clinical outcomes. One approach to promoting timely translation is to examine successful cases in order to understand facilitators and strategies for overcoming barriers. We examined the development of evidence-based management for neonatal abstinence syndrome (NAS) at one academic medical center, with a primary focus on pharmacologic treatment. Despite a substantial increase in NAS case incidence starting in the early 2000s, significant sociocultural, policy, and regulatory barriers limited collaborative NAS research. Facilitators for translation encompassed: 1) pursuing research of societal interest, 2) building an effective interdisciplinary team, 3) intentionally linking clinical, r

SUBMITTER: Brewer SK 

PROVIDER: S-EPMC9393572 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature