Clinical Implementation of NGAL Testing to Improve Diagnostic Assessment of AKI Episodes in a Canadian Center.

ABSTRACT:

Background

The differential diagnosis of acute kidney injury (AKI) episodes is often challenging. Novel AKI biomarkers have shown their utility to improve prognostic prediction and diagnostic assessment in various research populations but their implementation in standard clinical practice is still rarely reported.

Objective

To report the differential diagnostic ability and associated clinical utility of the neutrophil gelatinase-associated lipocalin (NGAL) testing in a real-life setting of a heterogeneous AKI population.

Design

This is a retrospective cohort study combined with a clinical audit using questionnaires distributed to consultant nephrologists following NGAL results.

Setting

The first 250 consecutive patients with a confirmed AKI where an NGAL test (

SUBMITTER: Cote JM 

PROVIDER: S-EPMC9393659 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature