Suboptimal states and frontoparietal network-centered incomplete compensation revealed by dynamic functional network connectivity in patients with post-stroke cognitive impairment.

ABSTRACT:

Background

Neural reorganization occurs after a stroke, and dynamic functional network connectivity (dFNC) pattern is associated with cognition. We hypothesized that dFNC alterations resulted from neural reorganization in post-stroke cognitive impairment (PSCI) patients, and specific dFNC patterns characterized different pathological types of PSCI.

Methods

Resting-state fMRI data were collected from 16 PSCI patients with hemorrhagic stroke (hPSCI group), 21 PSCI patients with ischemic stroke (iPSCI group), and 21 healthy controls (HC). We performed the dFNC analysis for the dynamic connectivity states, together with their topological and temporal features.

Results

We identified 10 resting-state networks (RSNs), and the dFNCs could be clustered into four reoccurring st

SUBMITTER: Rao B 

PROVIDER: S-EPMC9393744 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature