Super-refractory status epilepticus in adults.

ABSTRACT:

Introduction

Super-refractory status epilepticus (SRSE) represents the culmination of refractory status epilepticus (RSE) and carries a significant risk of poor neurological outcome and high mortality. RSE is not defined primarily by seizure duration, but by failure to respond to appropriate antiseizure treatment. SRSE is present when a RSE persists or recurs after more than 24 h of treatment with anesthetics. No evidence-based treatment algorithms can be provided for SRSE. Therefore, we propose a pragmatic standard operating procedure (SOP) for the management of SRSE that addresses the existing uncertainties in the treatment of SRSE and provides options for resolution and decision-making.

Comments

First, we recommend the assessment of persistent seizure activity and the eva

SUBMITTER: Malter MP 

PROVIDER: S-EPMC9394073 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature