Prognostic value of SOX9 in cervical cancer: Bioinformatics and experimental approaches.

ABSTRACT: Among gynecological cancers, cervical cancer is a common malignancy and remains the leading cause of cancer-related death for women. However, the exact molecular pathogenesis of cervical cancer is not known. Hence, understanding the molecular mechanisms underlying cervical cancer pathogenesis will aid in the development of effective treatment modalities. In this research, we attempted to discern candidate biomarkers for cervical cancer by using multiple bioinformatics approaches. First, we performed differential expression analysis based on cervical squamous cell carcinoma and endocervical adenocarcinoma data from The Cancer Genome Atlas database, then used differentially expressed genes for weighted gene co-expression network construction to find the most relevant gene module for cervical

SUBMITTER: Chen H 

PROVIDER: S-EPMC9394184 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature