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Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study.


ABSTRACT: This study provides updated information on the prevalence and co-infections caused by genital microorganisms and pathogens: Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, Ureaplasma urealyticum, Trichomonas vaginalis, and Gardnerella vaginalis, by retrospectively analyzing a cohort of patients living in the Naples metropolitan area, Campania region, Southern Italy. To investigate the genital infections prevalence in clinical specimens (vaginal/endocervical swabs and urines) collected from infertile asymptomatic women and men from November 2018 to December 2020, we used a multiplex real-time PCR assay. Of the 717 specimens collected, 302 (42.1%) resulted positive for at least one of the targets named above. Statistically significant differences in genital prevalence of selected microorganisms were detected in both women (62.91%) and men (37.08%). G. vaginalis and U. parvum represented the most common findings with an 80.2% and 16.9% prevalence in vaginal/endocervical swabs and first-voided urines, respectively. Prevalence of multiple infections was 18.18% and 8.19% in women and men, respectively. The most frequent association detected was the co-infection of G. vaginalis and U. parvum with 60% prevalence. Our epidemiological analysis suggests different infection patterns between genders, highlighting the need to implement a preventative screening strategy of genital infections to reduce the complications on reproductive organs.

SUBMITTER: Scaglione E 

PROVIDER: S-EPMC9394247 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study.

Scaglione Elena E   Mantova Giuseppe G   Caturano Valeria V   Fanasca Luca L   Carraturo Francesca F   Farina Fabrizio F   Pagliarulo Caterina C   Vitiello Mariateresa M   Pagliuca Chiara C   Salvatore Paola P   Colicchio Roberta R  

Diagnostics (Basel, Switzerland) 20220725 8


This study provides updated information on the prevalence and co-infections caused by genital microorganisms and pathogens: <i>Mycoplasma genitalium</i>, <i>Mycoplasma hominis, Ureaplasma parvum</i>, <i>Ureaplasma urealyticum</i>, <i>Trichomonas vaginalis</i>, and <i>Gardnerella vaginalis</i>, by retrospectively analyzing a cohort of patients living in the Naples metropolitan area, Campania region, Southern Italy. To investigate the genital infections prevalence in clinical specimens (vaginal/en  ...[more]

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