A Fusion Biopsy Framework for Prostate Cancer Based on Deformable Superellipses and nnU-Net.

ABSTRACT: In prostate cancer, fusion biopsy, which couples magnetic resonance imaging (MRI) with transrectal ultrasound (TRUS), poses the basis for targeted biopsy by allowing the comparison of information coming from both imaging modalities at the same time. Compared with the standard clinical procedure, it provides a less invasive option for the patients and increases the likelihood of sampling cancerous tissue regions for the subsequent pathology analyses. As a prerequisite to image fusion, segmentation must be achieved from both MRI and TRUS domains. The automatic contour delineation of the prostate gland from TRUS images is a challenging task due to several factors including unclear boundaries, speckle noise, and the variety of prostate anatomical shapes. Automatic methodologies, such as those

SUBMITTER: Altini N 

PROVIDER: S-EPMC9394419 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature