Medication Use in the Neonatal Intensive Care Unit and Changes from 2010 to 2018.

ABSTRACT:

Objective

To provide up-to-date medication prescribing patterns in US neonatal intensive care units (NICUs) and to examine trends in prescribing patterns over time.

Study design

We performed a cohort study of 799 016 infants treated in NICUs managed by the Pediatrix Medical Group from 2010 to 2018. We used 3 different methods to report counts of medication: exposure, courses, and days of use. We defined the change in frequency of medication administration by absolute change and relative change. We examined the Food and Drug Administration (FDA) package insert for each medication to determine whether a medication was labeled for use in infants and used PubMed to search for pharmacokinetics (PK) studies.

Results

The most frequently prescribed medications included ampici

SUBMITTER: Stark A 

PROVIDER: S-EPMC9394450 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature