Immunobiological Characteristics of the Attenuated African Swine Fever Virus Strain Katanga-350.

ABSTRACT: The African swine fever virus (ASFV) is the cause of a recent pandemic that is threatening the global pig industry. The virus infects domestic and wild pigs and manifests with a variety of clinical symptoms, depending on the strain. No commercial vaccine is currently available to protect animals from this virus, but some attenuated and recombinant live vaccine candidates might be effective against the disease. This article describes the immunobiological characteristics of one such candidate-the laboratory-attenuated ASFV strain, Katanga-350-which belongs to genotype I. In this study, we assessed clinical signs and post-mortem changes, the levels of viremia and the presence of viral DNA caused by injection of ASF virus strains Katanga-350, Lisbon-57, and Stavropol 08/01. Intramuscular injec

SUBMITTER: Sereda AD 

PROVIDER: S-EPMC9394480 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature