Genetic characterization of <i>Salmonella</i> Infantis from South Africa, 2004-2016.

ABSTRACT: Salmonella Infantis is presenting an increasing risk to public health. Of particular concern are the reports of pESI, a multidrug resistance (MDR) encoding megaplasmid, in isolates from multiple countries, but little is known about its presence or diversity in South Africa. Whole genome sequences of 387 S. Infantis isolates from South Africa (2004-2020) were analysed for genetic phylogeny, recombination frequency, antimicrobial resistance (AMR) determinants, plasmid presence and overall gene content. The population structure of South African S. Infantis was substantially different to S. Infantis reported elsewhere; only two thirds of isolates belonged to eBG31, while the remainder were identified as eBG297, a much rarer group globally. Significantly higher level

SUBMITTER: Mattock J 

PROVIDER: S-EPMC9394735 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature