Dicationic styryl dyes for colorimetric and fluorescent detection of nucleic acids.

ABSTRACT: Nucleic acid staining dyes are important tools for the analysis and visualizing of DNA/RNA in vitro and in the cells. Nevertheless, the range of commercially accessible dyes is still rather limited, and they are often very costly. As a result, finding nontoxic, easily accessible dyes, with desirable optical characteristics remains important. Styryl dyes have recently gained popularity as potential biological staining agents with many appealing properties, including a straightforward synthesis procedure, excellent photostability, tunable fluorescence, and high fluorescence quantum yield in the presence of nucleic acid targets with low background fluorescence signals. In addition to fluorescence, styryl dyes are strongly colored and exhibit solvatochromic properties which make them useful as

SUBMITTER: Supabowornsathit K 

PROVIDER: S-EPMC9395382 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature