Association between antidepressant use and ED or hospital visits in outpatients with SARS-CoV-2.

ABSTRACT: Antidepressants have previously been associated with better outcomes in patients hospitalized with COVID-19, but their effect on clinical deterioration among ambulatory patients has not been fully explored. The objective of this study was to assess whether antidepressant exposure was associated with reduced emergency department (ED) or hospital visits among ambulatory patients with SARS-CoV-2 infection. This retrospective cohort study included adult patients (N = 25 034) with a positive SARS-CoV-2 test performed in a non-hospital setting. Logistic regression analyses tested associations between home use of antidepressant medications and a composite outcome of ED visitation or hospital admission within 30 days. Secondary exposures included individual antidepressants and antidepressants with

SUBMITTER: Fritz BA 

PROVIDER: S-EPMC9395392 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature