Creatinine-based GFR-estimating equations in children with overweight and obesity.

ABSTRACT:

Background

With the increasing prevalence of childhood obesity and related development of chronic kidney disease (CKD), there is a critical need to understand how best to assess kidney function in children with obesity. Since serum creatinine (SCr) is recommended as marker of first choice for GFR estimation, we evaluated and compared creatinine-based GFR equations in children with overweight and obesity.

Methods

Six hundred children with overweight and obesity (53.5% female; mean age 12.20 ± 3.28 years; mean BMI z-score 3.31 ± 0.75) were included from the Centre for Overweight Adolescent and Children's Healthcare (COACH).

Results

Serum creatinine (SCr), normalized using Q-age polynomials obtained from reference values, results in median and mean SCr/Q value close to "

SUBMITTER: van Dam MJCM 

PROVIDER: S-EPMC9395456 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature