Influence of right coronary artery motion, flow pulsatility and non-Newtonian rheology on wall shear stress metrics.

ABSTRACT: The patchy distribution of atherosclerosis within the arterial system is consistent with a controlling influence of hemodynamic wall shear stress (WSS). Patterns of low, oscillatory and transverse WSS have been invoked to explain the distribution of disease in the aorta. Disease of coronary arteries has greater clinical importance but blood flow in these vessels may be complicated by their movement during the cardiac cycle. Previous studies have shown that time average WSS is little affected by the dynamic geometry, and that oscillatory shear is influenced more. Here we additionally investigate effects on transverse WSS. We also investigate the influence of non-Newtonian blood rheology as it can influence vortical structure, on which transverse WSS depends; Carreau-Yasuda models were used.

SUBMITTER: Kandangwa P 

PROVIDER: S-EPMC9395597 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature