Prospective evaluation of ¹⁸F-FDG positron emission tomography in the preoperative staging of patients with hepatic colorectal metastases.

ABSTRACT:

Background

Despite considerable advances in preoperative imaging, up to one-third of patients operatively explored for hepatic colorectal metastases are unexpectedly found to harbor unresectable intrahepatic or extrahepatic disease.

Methods

The current study is a prospective, blinded study comparing utility of [¹⁸F]2-fluoro-2-deoxyglucose positron emission tomography (¹⁸F-FDG-PET) to computed tomography (CT) and CT arterial portography (CTAP) as preoperative staging.

Results

The 125 planned subjects were enrolled. Findings seen on FDG-PET alone changed therapy for 23 of 125 patients (18%). FDG-PET confirmed other radiologic findings in 16 cases (13%), for an overall influence on therapy in 39 cases (31%). FDG-PET was the most sensitive diagnostic

SUBMITTER: Akhurst T 

PROVIDER: S-EPMC9396102 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature