Identification of injury type using somatosensory and motor evoked potentials in a rat spinal cord injury model.

ABSTRACT: The spinal cord is at risk of injury during spinal surgery. If intraoperative spinal cord injury is identified early, irreversible impairment or loss of neurological function can be prevented. Different types of spinal cord injury result in damage to different spinal cord regions, which may cause different somatosensory and motor evoked potential signal responses. In this study, we examined electrophysiological and histopathological changes between contusion, distraction, and dislocation spinal cord injuries in a rat model. We found that contusion led to the most severe dorsal white matter injury and caused considerable attenuation of both somatosensory and motor evoked potentials. Dislocation resulted in loss of myelinated axons in the lateral region of the injured spinal cord along the r

SUBMITTER: Li R 

PROVIDER: S-EPMC9396501 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature