[Pt(PPh₃)₄]-Catalyzed Selective Diboration of Symmetrical and Unsymmetrical 1,3-Diynes.

ABSTRACT: A straightforward, efficient, and selective method for the preparation of novel boryl-functionalized enynes or dienes via [Pt(PPh₃)₄]-catalyzed diboration of a broad spectrum of symmetrical and unsymmetrical 1,3-diynes was developed. The catalytic cycle of diboration was proposed on the basis of low-temperature ³¹P NMR studies. An alternative isolation method via product condensation on a cold finger was developed, which, in contrast to previous literature reports, eliminates the need for the additional transformation of rapidly decomposing enynyl pinacol boronates to more stable silica-based column chromatography derivatives during the separation step. To prove the efficiency of this simple catalytic protocol, bisboryl-functionalized enynes were synthesize

SUBMITTER: Szyling J 

PROVIDER: S-EPMC9396666 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature