Urine D-ribose levels correlate with cognitive function in community-dwelling older adults.

ABSTRACT:

Background

D-ribose is involved in the pathogenesis of Alzheimer's Disease. The study aimed to determine the association between D-ribose and cognitive function in a sample of community-dwelling older adults.

Methods

A cross-sectional study was conducted in Chaoyang District, Beijing in 2019-2020. Eligible participants were community-based older adults aged 60 years and above. D-ribose was analyzed from the morning urine. Cognitive function, subjective cognitive decline, and depressive symptoms were measured by a battery of neuropsychological tests. Linear regressions were performed to determine the relationship between the urine D-ribose levels and cognitive performance.

Results

A sample of 1725 participants (67.1% female) aged 60 to 85 years (69.40 ± 5.87 years, mea

SUBMITTER: Zhu X 

PROVIDER: S-EPMC9396817 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature