Multimodal targeting of glioma with functionalized nanoparticles.

ABSTRACT: The most common and aggressive primitive intracranial tumor of the central nervous system is the glioma. The blood-brain barrier (BBB) has proven to be a significant obstacle to the effective treatment of glioma. To effectively treat glioma, different ways have been used to cross the BBB to deliver drugs to the brain. Drug delivery through nanocarriers proves to be an effective and non-invasive technique for the treatment of glioma and has great potential in the treatment of glioma. In this review, we will provide an overview of nanocarrier-mediated drug delivery and related glioma therapy. Nanocarrier-mediated drug delivery techniques to cross the BBB (liposomes, micelles, inorganic systems, polymeric nanoparticles, nanogel system, and biomimetic nanoparticles) are explored. Finally, the

SUBMITTER: Marei HE 

PROVIDER: S-EPMC9396820 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature