Decreased haemoglobin levels are associated with lower muscle mass and strength in kidney transplant recipients.

ABSTRACT:

Background

Post-transplant anaemia and reduced muscle mass and strength are highly prevalent in kidney transplant recipients (KTRs). Decreased haemoglobin levels, a marker of anaemia, could adversely affect muscle mass and strength through multiple mechanisms, among others, through diminished tissue oxygenation. We aimed to investigate the association between haemoglobin levels with muscle mass and strength in KTRs.

Methods

We included stable KTRs from the TransplantLines Biobank and Cohort study with a functional graft ≥1 year post-transplantation. Muscle mass was assessed using 24 h urinary creatinine excretion rate (CER) and bioelectrical impedance analysis (BIA). Muscle strength was assessed with a handgrip strength test using a dynamometer and, in a subgroup (n = 290),

SUBMITTER: Vinke JSJ 

PROVIDER: S-EPMC9397498 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature