Individuality and ethnicity eclipse a short-term dietary intervention in shaping microbiomes and viromes.

ABSTRACT: Many diseases linked with ethnic health disparities associate with changes in microbial communities in the United States, but the causes and persistence of ethnicity-associated microbiome variation are not understood. For instance, microbiome studies that strictly control for diet across ethnically diverse populations are lacking. Here, we performed multiomic profiling over a 9-day period that included a 4-day controlled vegetarian diet intervention in a defined geographic location across 36 healthy Black and White females of similar age, weight, habitual diets, and health status. We demonstrate that individuality and ethnicity account for roughly 70% to 88% and 2% to 10% of taxonomic variation, respectively, eclipsing the effects a short-term diet intervention in shaping gut and oral micr

SUBMITTER: Li J 

PROVIDER: S-EPMC9397868 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature